Using Genetically Engineered Mice to Probe the Role of Bioactive Lipids in Prostate Carcinogenesis
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The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model
Increasing evidence from epidemiological and pathological studies suggests a role of the immune system in the initiation and progression of multiple cancers, including prostate cancer. Reports on the contribution of the adaptive immune system are contradictive, since both suppression and acceleration of disease development have been reported. This study addresses the functional role of lymphocy...
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